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Titre de l’article EEG biological correlates of hypervigilance mediate maternal interpersonal violence-related PTSD and child psychopathology
Code d’article P14
Auteurs
  1. Virginie Pointet Faculty of Medicine, UNIGE Conférencier
  2. Marie-Pierre Deiber Faculty of Medicine, UNIGE
  3. Dominik A. Moser CHUV
  4. Marylène Vital Department head, Direction de la protection des mineurs (SPMI)
  5. Sandra Rusconi Serpa Faculty of Psychology, UniGe
  6. Tomas Ros Faculty of Medicine, UNIGE
  7. Daniel S. Schechter CHUV centre hospitalier universitaire vaudois Conférencier
Forme de présentation Poster
Domaines thématiques
  • T14 - Neuroimaging, Neuroscience & Neurotherapies
Résumé (Abstract) Introduction:
Previous results obtained in the present longitudinal study demonstrated that mothers’ interpersonal violence-related posttraumatic stress disorder (IPV-PTSD) affects their own child emotional appraisal of negative emotions recorded with EEG during an Emotional Face Matching Task (EFMT). In the present research, we considered if child resting state (RS) EEG might also be a biological correlate of hypervigilance, that mediates maternal IPV-PTSD and child psychopathology.
Methods:
RS was recorded with eyes-closed for a 3-minute period in a sample of 59 children (34 of IPV-PTSD mothers and 23 non-PTSD controls) and their mothers. Spectral power in alpha and beta bands as well as the slope of the power spectrum, also known as the PLE (power-law exponent) were considered in our analyses as mediators of maternal IPV-PTSD and child psychopathology. PLE has been previously shown to be an electrophysiological correlate of cortical excitability and behavioral arousal/vigilance.
Results:
Results first showed that in children from mother’s with PTSD, PLE was significantly attenuated compared to control children (Cohen’s d = -0.7, p < 0.05), indicating cortical hyper-arousal. Intriguingly, their PLE was associated with maternal IPV-PTSD severity, measured using the CAPS. Considering intergenerational transmission, we also found an association between child PLE and child separation anxiety and PTSD symptoms, measured using the K-SADS, as well as with child relational bullying measured using the School-Life Survey. Finally, mediation analyses were performed, and models showed that 1) child PLE mediated maternal PTSD severity and child anxiety, and 2) child PLE mediates maternal PTSD severity and child relational bullying. We also noted a direct effect of maternal PTSD severity on child PTSD symptoms, without any mediation of child PLE.
Discussion:
Our observations indicate that maternal IPV-PTSD affects child anxiety and behavior, via child PLE, a biological correlate of hypervigilance. These findings are of potential relevance to the development of more effective parent-child interventions among families with interpersonal violence exposure.